PLEC antibody (AA 240-320)

Catalog No. ABIN7230686

The Rabbit Polyclonal anti-PLEC antibody (ABIN7230686) specifically detects PLEC in IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PLEC antibody (AA 240-320) (ABIN7230686)

Target: PLEC (Plectin (PLEC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLEC antibody is un-conjugated

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PLEC Antibody

Binding Specificity: AA 240-320

Purpose: Rabbit Anti-PLEC Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PLEC protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PLEC protein at AA range: 240-320

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLEC

Target: PLEC (Plectin (PLEC))

Alternative Name: PLEC

Background: Plectin, PCN, PLTN, Hemidesmosomal protein 1, HD1, Plectin-1PLEC (Plectin) is a Protein Coding gene. Diseases associated with PLEC include Epidermolysis Bullosa Simplex, Ogna Type and Muscular Dystrophy, Limb-Girdle, Type 2Q. Among its related pathways are Cytoskeleton remodeling Neurofilaments and Collagen chain trimerization. PLEC is a prominent member of an important family of structurally and in part functionally related proteins, termed plakins or cytolinkers, that are capable of interlinking different elements of the cytoskeleton.

Molecular Weight: 515kD

Gene ID: 5339

UniProt: Q15149