PLK1S1 antibody (AA 320-400)

Catalog No. ABIN7229294

The Rabbit Polyclonal anti-PLK1S1 antibody (ABIN7229294) specifically detects PLK1S1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for PLK1S1 antibody (AA 320-400) (ABIN7229294)

Target: PLK1S1 (Polo-Like Kinase 1 Substrate 1 (PLK1S1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLK1S1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLK1S1 Antibody

Binding Specificity: AA 320-400

Purpose: Rabbit Anti-KIZ Polyclonal Antibody

Specificity: The antibody detects endogenous levels of KIZ protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human KIZ protein at AA range: 320-400

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLK1S1

Target: PLK1S1 (Polo-Like Kinase 1 Substrate 1 (PLK1S1))

Alternative Name: KIZ

Background: Centrosomal protein kizuna, Polo-like kinase 1 substrate 1KIZ (Kizuna Centrosomal Protein) is a Protein Coding gene. Diseases associated with KIZ include Retinitis Pigmentosa 69 and Kiz-Related Retinitis Pigmentosa. Among its related pathways are PLK1 signaling events. The protein encoded by KIZ localizes to centrosomes, strengthening and stabilizing the pericentriolar region prior to spindle formation. The encoded protein usually remains with the mother centrosome after centrosomal duplication. Sevral transcript variants encoding different isoforms have been found for KIZ.

Molecular Weight: 74kD

Gene ID: 55857

UniProt: Q2M2Z5