PLK4 antibody

Catalog No. ABIN7230694

This Rabbit Polyclonal antibody specifically detects PLK4 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PLK4 antibody (ABIN7230694)

Target: PLK4 (Polo-Like Kinase 4 (PLK4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PLK4 Antibody

Purpose: Rabbit Anti-PLK4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PLK4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PLK4 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PLK4

Target: PLK4 (Polo-Like Kinase 4 (PLK4))

Alternative Name: PLK4

Target Type: Phage Protein

Background: Serine/threonine-protein kinase PLK4, Polo-like kinase 4, PLK-4, Serine/threonine-protein kinase 18, Serine/threonine-protein kinase SakPLK4 (Polo Like Kinase 4) is a Protein Coding gene. Among its related pathways are DNA Damage and Regulation of PLK1 Activity at G2/M Transition. PLK4 encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for PLK4.

Molecular Weight: 106kD

Gene ID: 10733

UniProt: O00444

Pathways: M Phase