PARP4 antibody (AA 1120-1200)

Catalog No. ABIN7219710

The Rabbit Polyclonal anti-PARP4 antibody (ABIN7219710) specifically detects PARP4 in IHC, ELISA and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for PARP4 antibody (AA 1120-1200) (ABIN7219710)

Target: PARP4 (Poly (ADP-Ribose) Polymerase Family, Member 4 (PARP4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP4 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PARP4 Antibody

Binding Specificity: AA 1120-1200

Purpose: Rabbit Anti-PARP-4 Polyclonal Antibody

Specificity: PARP-4 Polyclonal Antibody detects endogenous levels of PARP-4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PARP-4 at AA range: 1120-1200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PARP4

Target: PARP4 (Poly (ADP-Ribose) Polymerase Family, Member 4 (PARP4))

Alternative Name: PARP-4

Background: PARP4, ADPRTL1, KIAA0177, PARPL, Poly [ADP-ribose] polymerase 4, PARP-4, 193 kDa vault protein, ADP-ribosyltransferase diphtheria toxin-like 4, ARTD4, PARP-related/IalphaI-related H5/proline-rich, PH5P, Vault poly(ADP-ribose) polymerase, VPPARP4 encodes poly(ADP-ribosyl)transferase-like 1 protein, which is capable of catalyzing a poly(ADP-ribosyl)ation reaction. Poly [ADP-ribose] polymerase 4 has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. Since this protein is not capable of binding DNA directly, its transferase activity may be activated by other factors such as protein-protein interaction mediated by the extensive carboxyl terminus.

Gene ID: 143

UniProt: Q9UKK3