PABPC3 antibody (AA 330-410)

Catalog No. ABIN7222886

This Rabbit Polyclonal antibody specifically detects PABPC3 in WB, IHC, ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for PABPC3 antibody (AA 330-410) (ABIN7222886)

Target: PABPC3 (Poly(A) Binding Protein, Cytoplasmic 3 (PABPC3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PABPC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Product Details anti-PABPC3 Antibody

Binding Specificity: AA 330-410

Purpose: Rabbit Anti-PABP3 Polyclonal Antibody

Specificity: PABP3 Polyclonal Antibody detects endogenous levels of PABP3 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PABP3 at AA range: 330-410

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC:1:50-300,ELISA 1:20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PABPC3

Target: PABPC3 (Poly(A) Binding Protein, Cytoplasmic 3 (PABPC3))

Alternative Name: PABP3

Background: PABPC3, PABP3, PABPL3, Polyadenylate-binding protein 3, PABP-3, Poly(A)-binding protein 3, Testis-specific poly(A)-binding proteinPABPC3 encodes a poly (A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly (A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly (A) promotes ribosome recruitment and translation initiation, it is also required for poly (A) shortening which is the first step in mRNA decay. PABPC3 is part of a small gene family including three protein-coding genes and several pseudogenes.

Molecular Weight: 70kD

Gene ID: 5042

UniProt: Q9H361