PKD1/2/3 antibody (pSer738)

Catalog No. ABIN7223542

The Rabbit Polyclonal anti-PKD1/2/3 antibody (ABIN7223542) specifically detects PKD1/2/3 in ELISA, WB, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PKD1/2/3 antibody (pSer738) (ABIN7223542)

Target: PKD1/2/3 (Polycystic Kidney Disease 1/2/3 (PKD1/2/3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKD1/2/3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PKD1/2/3 Antibody

Binding Specificity: pSer738

Purpose: Rabbit Anti-PKD1/2/3 (phospho Ser738/S742) Polyclonal Antibody

Specificity: Phospho-PKD1/2/3 (S738/S742) Polyclonal Antibody detects endogenous levels of PKD1/2/3 protein only when phosphorylated at S738/S742.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human PKD1/2/3 Phospho-Ser738/S742

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PKD1/2/3

Target: PKD1/2/3 (Polycystic Kidney Disease 1/2/3 (PKD1/2/3))

Alternative Name: PKD1/2/3

Background: PRKD1, PKD, PKD1, PRKCM, Serine/threonine-protein kinase D1, Protein kinase C mu type, Protein kinase D, nPKC-D1, nPKC-mu, PRKD2, PKD2, HSPC187, Serine/threonine-protein kinase D2, nPKC-D2, PRKD3, EPK2, PRKCN, Serine/threonine-protein kinasPRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and regulation of cell shape, motility, and adhesion.

Molecular Weight: 101kD

Gene ID: 5587, 25865, 23683

UniProt: Q15139, Q9BZL6, O94806