POLM antibody (AA 210-290)

Catalog No. ABIN7217760

This anti-POLM antibody is a Rabbit Polyclonal antibody detecting POLM in WB and ELISA. Suitable for Human.

Quick Overview for POLM antibody (AA 210-290) (ABIN7217760)

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLM antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLM Antibody

Binding Specificity: AA 210-290

Purpose: DNA Pol μ Polyclonal Antibody

Specificity: DNA Pol μ Polyclonal Antibody detects endogenous levels of DNA Pol μ protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human DNA Pol mu at AA range: 210-290

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for POLM

Target: POLM (Polymerase (DNA Directed), mu (POLM))

Alternative Name: DNA Pol mu

Background: Rabbit Anti-DNA Pol μ Polyclonal Antibody,POLM, polmu, DNA-directed DNA/RNA polymerase mu, Pol Mu, Terminal transferase,POLM (Polymerase (DNA) Mu) is a Protein Coding gene. Among its related pathways are Platinum Pathway, Pharmacokinetics/Pharmacodynamics and DNA Double-Strand Break Repair. Gene Ontology (GO) annotations related to this gene include DNA-directed DNA polymerase activity and DNA polymerase activity. An important paralog of this gene is POLB. Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.,DNA-directed DNA

Molecular Weight: observerd band 54kDa

Gene ID: 27434

UniProt: Q9NP87

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response