POLE4 antibody (AA 30-110)

Catalog No. ABIN7223666

The Rabbit Polyclonal anti-POLE4 antibody is suitable to detect POLE4 in samples from Human and Mouse. It has been validated for ELISA and IHC (p).

Quick Overview for POLE4 antibody (AA 30-110) (ABIN7223666)

Target: POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLE4 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-POLE4 Antibody

Binding Specificity: AA 30-110

Purpose: DNA pol ε 4 Polyclonal Antibody

Specificity: DNA pol ε 4 Polyclonal Antibody detects endogenous levels of DNA pol ε 4 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human DNA pol epsilon 4 at AA range: 30-110

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for POLE4

Target: POLE4 (Polymerase (DNA-Directed), epsilon 4 (p12 Subunit) (POLE4))

Alternative Name: DNA pol epsilon 4

Background: Rabbit Anti-DNA pol ε 4 Polyclonal Antibody,POLE4, DNA polymerase epsilon subunit 4, DNA polymerase II subunit 4, DNA polymerase epsilon subunit p12,POLE4 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.,DNA polymerase epsilon subunit 4

Molecular Weight: observerd band 12kDa

Gene ID: 56655

UniProt: Q9NR33

Pathways: DNA Damage Repair