POLR1D antibody

Catalog No. ABIN7231142

The Rabbit Polyclonal anti-POLR1D antibody is suitable to detect POLR1D in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for POLR1D antibody (ABIN7231142)

Target: POLR1D (Polymerase (RNA) I Polypeptide D, 16kDa (POLR1D))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLR1D antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POLR1D Antibody

Purpose: Rabbit Anti-RPAC2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RPAC2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RPAC2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for POLR1D

Target: POLR1D (Polymerase (RNA) I Polypeptide D, 16kDa (POLR1D))

Alternative Name: RPAC2

Background: POLR1D encoded by this gene is a component of the RNA polymerase I and RNA polymerase III complexes, which function in the synthesis of ribosomal RNA precursors and small RNAs, respectively. Mutations in this gene are a cause of Treacher Collins syndrome (TCS), a craniofacial development disorder. Alternative splicing results in multiple transcript variants. POLR1D (RNA Polymerase I Subunit D) is a Protein Coding gene. Diseases associated with POLR1D include Treacher Collins Syndrome 2 and Polr1d-Related Treacher Collins Syndrome. Among its related pathways are Pyrimidine metabolism (KEGG) and RNA Polymerase III Transcription Initiation.

Molecular Weight: 14kD

Gene ID: 51082

UniProt: Q9Y2S0