KCNK17 antibody (AA 240-320)

Catalog No. ABIN7225744

The Rabbit Polyclonal anti-KCNK17 antibody is suitable to detect KCNK17 in samples from Human. It has been validated for WB and ELISA.

Quick Overview for KCNK17 antibody (AA 240-320) (ABIN7225744)

Target: KCNK17 (Potassium Channel, Subfamily K, Member 17 (KCNK17))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK17 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KCNK17 Antibody

Binding Specificity: AA 240-320

Purpose: Rabbit Anti-TALK-2 Polyclonal Antibody

Specificity: TALK-2 Polyclonal Antibody detects endogenous levels of TALK-2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human TALK-2 at AA range: 240-320

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KCNK17

Target: KCNK17 (Potassium Channel, Subfamily K, Member 17 (KCNK17))

Alternative Name: TALK-2

Background: KCNK17, TALK2, TASK4, Potassium channel subfamily K member 17, 2P domain potassium channel Talk-2, Acid-sensitive potassium channel protein TASK-4, TWIK-related acid-sensitive K(+) channel 4, TWIK-related alkaline pH -activated K(+) channelThe protein encoded by KCNK17 (potassium two pore domain channel subfamily K member 17) belongs to the family of potassium channel proteins containing two pore-forming P domains. This channel is an open rectifier which primarily passes outward current under physiological K+ concentrations. KCNK17 is activated at alkaline pH . Alternatively spliced transcript variants encoding different isoforms have been found for KCNK17.

Molecular Weight: 37-42kD

Gene ID: 89822

UniProt: Q96T54