KCNK3 antibody (N-Term)

Catalog No. ABIN7226640

The Rabbit Polyclonal anti-KCNK3 antibody (ABIN7226640) specifically detects KCNK3 in WB and ELISA. The antibody is reactive with Rat, Human and Mouse samples.

Quick Overview for KCNK3 antibody (N-Term) (ABIN7226640)

Target: KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KCNK3 Antibody

Binding Specificity: N-Term

Purpose: Rabbit Anti-TASK-1 Polyclonal Antibody

Specificity: TASK-1 Polyclonal Antibody detects endogenous levels of TASK-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human TASK-1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KCNK3

Target: KCNK3 (Potassium Channel, Subfamily K, Member 3 (KCNK3))

Alternative Name: TASK-1

Background: KCNK3, TASK, TASK1, Potassium channel subfamily K member 3, Acid-sensitive potassium channel protein TASK-1, TWIK-related acid-sensitive K(+) channel 1, Two pore potassium channel KT3.1, Two pore K(+) channel KT3.1KCNK3 (potassium two pore domain channel subfamily K member 3) encodes a member of the superfamily of potassium channel proteins that contain two pore-forming P domains. The encoded protein is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for KCNK3.

Molecular Weight: 53kD

Gene ID: 3777

UniProt: O14649