KCNK4 antibody (AA 310-390)

Catalog No. ABIN7217364

The Rabbit Polyclonal anti-KCNK4 antibody has been validated for WB and ELISA. It is suitable to detect KCNK4 in samples from Human and Mouse.

Quick Overview for KCNK4 antibody (AA 310-390) (ABIN7217364)

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNK4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-KCNK4 Antibody

Binding Specificity: AA 310-390

Purpose: TRAAK Polyclonal Antibody

Specificity: TRAAK Polyclonal Antibody detects endogenous levels of TRAAK protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human TRAAK at AA range: 310-390

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for KCNK4

Target: KCNK4 (Potassium Channel, Subfamily K, Member 4 (KCNK4))

Alternative Name: TRAAK

Background: Rabbit Anti-TRAAK Polyclonal Antibody,KCNK4, TRAAK, Potassium channel subfamily K member 4, TWIK-related arachidonic acid-stimulated potassium channel protein, TRAAK, Two pore potassium channel KT4.1, Two pore K(+) channel KT4.1,KCNK4 encodes a member of the TWIK-related arachidonic acid-stimulated two pore potassium channel subfamily. The potassium channel subfamily K member 4 homodimerizes and functions as an outwardly rectifying channel. This channel is regulated by polyunsaturated fatty acids, temperature and mechanical deformation of the lipid membrane. Potassium channel subfamily K member 4 is expressed primarily in neural tissues and may be involved in regulating the noxious input threshold in dorsal root ganglia neurons. Alternate splicing results in multiple transcript variants. Naturally occurring read-through transcripts also exist between this gene and the downstream testis expressed 40 (TEX40) gene, as represented in GeneID: 106780802.,Potassium channel subfamily K member 4

Molecular Weight: observerd band 45kDa

Gene ID: 50801

UniProt: Q9NYG8