KCNV2 antibody (AA 160-240)

Catalog No. ABIN7220028

This Rabbit Polyclonal antibody specifically detects KCNV2 in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for KCNV2 antibody (AA 160-240) (ABIN7220028)

Target: KCNV2 (Potassium Channel, Subfamily V, Member 2 (KCNV2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNV2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-KCNV2 Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-KV8.2 Polyclonal Antibody

Specificity: KV8.2 Polyclonal Antibody detects endogenous levels of KV8.2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human KV8.2 at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for KCNV2

Target: KCNV2 (Potassium Channel, Subfamily V, Member 2 (KCNV2))

Alternative Name: KV8.2

Background: KCNV2, Potassium voltage-gated channel subfamily V member 2, Voltage-gated potassium channel subunit Kv8.2Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNV2 encodes a member of the potassium voltage-gated channel subfamily V. This member is identified as a 'silent subunit', and it does not form homomultimers, but forms heteromultimers with several other subfamily members. Through obligatory heteromerization, it exerts a function-altering effect on other potassium channel subunits. This protein is strongly expressed in pancreas and has a weaker expression in several other tissues.

Molecular Weight: 62kD

Gene ID: 169522

UniProt: Q8TDN2