PJA1 antibody

Catalog No. ABIN7230658

The Rabbit Polyclonal anti-PJA1 antibody (ABIN7230658) specifically detects PJA1 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for PJA1 antibody (ABIN7230658)

Target: PJA1 (Praja Ring Finger 1, E3 Ubiquitin Protein Ligase (PJA1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PJA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PJA1 Antibody

Purpose: Rabbit Anti-PJA1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PJA1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PJA1 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PJA1

Target: PJA1 (Praja Ring Finger 1, E3 Ubiquitin Protein Ligase (PJA1))

Alternative Name: PJA1

Background: E3 ubiquitin-protein ligase Praja-1, Praja1, RING finger protein 70, RING-type E3 ubiquitin transferase Praja-1PJA1 encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked cognitive disability disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants.

Molecular Weight: 70kD

Gene ID: 64219

UniProt: Q8NG27