PZP antibody (AA 1301-1350)
Quick Overview for PZP antibody (AA 1301-1350) (ABIN7230862)
Target
See all PZP AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1301-1350
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Purpose
- PZP Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of PZP protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human PZP protein at AA range: 1301-1350
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- PZP (Pregnancy Zone Protein (PZP))
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Alternative Name
- PZP
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Background
- Rabbit Anti-PZP Polyclonal Antibody,Pregnancy zone protein, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 6,Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.,PZP
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Molecular Weight
- observerd band 163kDa
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Gene ID
- 5858
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UniProt
- P20742
Target
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