PAQR8 antibody (AA 280-360)

Catalog No. ABIN7229746

The Rabbit Polyclonal anti-PAQR8 antibody (ABIN7229746) specifically detects PAQR8 in WB and ELISA. The antibody is reactive with Mouse and Human samples.

Quick Overview for PAQR8 antibody (AA 280-360) (ABIN7229746)

Target: PAQR8 (Progestin and AdipoQ Receptor Family Member VIII (PAQR8))

Reactivity: Mouse, Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAQR8 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PAQR8 Antibody

Binding Specificity: AA 280-360

Purpose: Rabbit Anti-MPRB Polyclonal Antibody

Specificity: The antibody detects endogenous levels of MPRB protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MPRB protein at AA range: 280-360

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PAQR8

Target: PAQR8 (Progestin and AdipoQ Receptor Family Member VIII (PAQR8))

Alternative Name: MPRB

Background: Membrane progestin receptor beta, mPR beta, Lysosomal membrane protein in brain 1, Membrane progesterone P4 receptor beta, Membrane progesterone receptor beta, Progesterone and adipoQ receptor family member 8, Progestin and adipoQ receptor family member 8, Progestin and adipoQ receptor family member VIIIPlasma membrane progesterone (P4) receptor coupled to G proteins (PubMed: 23763432). Seems to act through a G(i) mediated pathway (PubMed: 23763432). May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone (PubMed: 23161870).

Molecular Weight: 38kD

Gene ID: 85315

UniProt: Q8TEZ7