Prohibitin 2 antibody

Catalog No. ABIN7230616

This anti-Prohibitin 2 antibody is a Rabbit Polyclonal antibody detecting Prohibitin 2 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for Prohibitin 2 antibody (ABIN7230616)

Target: Prohibitin 2 (PHB2)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prohibitin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Prohibitin 2 Antibody

Purpose: PHB2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PHB2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PHB2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Prohibitin 2

Target: Prohibitin 2 (PHB2)

Alternative Name: PHB2

Background: Rabbit Anti-PHB2 Polyclonal Antibody,B-cell receptor-associated protein BAP37, D-prohibitin, Repressor of estrogen receptor activity,PHB2 (Prohibitin 2) is a Protein Coding gene. Diseases associated with PHB2 include Urethritis and Loiasis. Among its related pathways are GPCR Pathway and MAPK Signaling: mitogen Stimulation Pathway. GO annotations related to this gene include estrogen receptor binding. Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.,PHB2

Molecular Weight: observerd band 32kDa

Gene ID: 11331

UniProt: Q99623

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling