Prolactin Receptor antibody (AA 80-160)

Catalog No. ABIN7230782

The Rabbit Polyclonal anti-Prolactin Receptor antibody has been validated for WB and ELISA. It is suitable to detect Prolactin Receptor in samples from Human, Rat and Mouse.

Quick Overview for Prolactin Receptor antibody (AA 80-160) (ABIN7230782)

Target: Prolactin Receptor (PRLR)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prolactin Receptor antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Prolactin Receptor Antibody

Binding Specificity: AA 80-160

Purpose: PRLR Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PRLR protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PRLR protein at AA range: 80-160

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for Prolactin Receptor

Target: Prolactin Receptor (PRLR)

Alternative Name: PRLR

Background: Rabbit Anti-PRLR Polyclonal Antibody,Prolactin receptor, PRL-R,PRLR encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for PRLR, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer.,PRLR

Molecular Weight: observerd band 68kDa

Gene ID: 5618

UniProt: P16471

Pathways: JAK-STAT Signaling, Response to Growth Hormone Stimulus