PTGIS antibody (C-Term)

Catalog No. ABIN7223746

The Rabbit Polyclonal anti-PTGIS antibody (ABIN7223746) specifically detects PTGIS in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PTGIS antibody (C-Term) (ABIN7223746)

Target: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTGIS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PTGIS Antibody

Binding Specificity: C-Term

Purpose: PGI2 synthase Polyclonal Antibody

Specificity: PGI2 synthase Polyclonal Antibody detects endogenous levels of PGI2 synthase protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human PGI2 synthase

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PTGIS

Target: PTGIS (Prostaglandin I2 (Prostacyclin) Synthase (PTGIS))

Alternative Name: PGI2 synthase

Background: Rabbit Anti-PGI2 synthase Polyclonal Antibody,PTGIS, CYP8, CYP8A1, Prostacyclin synthase, Prostaglandin I2 synthase,PTGIS (prostaglandin I2 (prostacyclin) synthase) encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.,Prostacyclin synthase

Molecular Weight: observerd band 57kDa

Gene ID: 5740

UniProt: Q16647