PRSS1 antibody (Internal Region)

Catalog No. ABIN7217396

The Rabbit Polyclonal anti-PRSS1 antibody is suitable to detect PRSS1 in samples from Human and Rat. It has been validated for WB and ELISA.

Quick Overview for PRSS1 antibody (Internal Region) (ABIN7217396)

Target: PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PRSS1 Antibody

Binding Specificity: Internal Region

Purpose: Rabbit Anti-Trypsin-1 Polyclonal Antibody

Specificity: Trypsin-1 Polyclonal Antibody detects endogenous levels of Trypsin-1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Trypsin-1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:10000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PRSS1

Target: PRSS1 (Protease, serine, 1 (Trypsin 1) (PRSS1))

Alternative Name: Trypsin-1

Background: PRSS1, TRP1, TRY1, TRYP1, Trypsin-1, Beta-trypsin, Cationic trypsinogen, Serine protease 1, Trypsin IPRSS1 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.

Molecular Weight: 23kD

Gene ID: 5644

UniProt: P07477