PRSS2 antibody (AA 40-120)

Catalog No. ABIN7231936

This anti-PRSS2 antibody is a Rabbit Polyclonal antibody detecting PRSS2 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for PRSS2 antibody (AA 40-120) (ABIN7231936)

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRSS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PRSS2 Antibody

Binding Specificity: AA 40-120

Purpose: TRY2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of TRY2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human TRY2 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PRSS2

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Alternative Name: TRY2

Background: Rabbit Anti-TRY2 Polyclonal Antibody,Anionic trypsinogen, Serine protease 2, Trypsin II,PRSS2 belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.,TRY2

Molecular Weight: observerd band 27kDa

Gene ID: 5645

UniProt: P07478