PRSS2 antibody

Catalog No. ABIN7269580

This Rabbit Monoclonal antibody specifically detects PRSS2 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for PRSS2 antibody (ABIN7269580)

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PRSS2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PRSS2 Antibody

Purpose: PRSS2 Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of human PRSS2.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for PRSS2

Target: PRSS2 (Protease, serine, 2 (Trypsin 2) (PRSS2))

Alternative Name: PRSS2

Background: This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.,PRSS2, TRY2, TRY8, TRYP2, trypsin-2,Cell Biology & Developmental Biology,Ubiquitin,PRSS2

Molecular Weight: 30kDa

Gene ID: 5645

UniProt: P07478