POT1 antibody (Internal Region)

Catalog No. ABIN7216628

This anti-POT1 antibody is a Rabbit Polyclonal antibody detecting POT1 in WB and ELISA. Suitable for Human and Monkey.

Quick Overview for POT1 antibody (Internal Region) (ABIN7216628)

Target: POT1 (Protection of Telomeres 1 (POT1))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-POT1 Antibody

Binding Specificity: Internal Region

Purpose: POT1 Polyclonal Antibody

Specificity: POT1 Polyclonal Antibody detects endogenous levels of POT1 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human POT1

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for POT1

Target: POT1 (Protection of Telomeres 1 (POT1))

Alternative Name: POT1

Background: Rabbit Anti-POT1 Polyclonal Antibody,POT1, Protection of telomeres protein 1, hPot1, POT1-like telomere end-binding protein,POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.,Protection of telomeres protein 1

Molecular Weight: observerd band 70kDa

Gene ID: 25913

UniProt: Q9NUX5

Pathways: Cell Division Cycle, Telomere Maintenance