AMNLS antibody

Catalog No. ABIN7227278

The Rabbit Polyclonal anti-AMNLS antibody is suitable to detect AMNLS in samples from Human and Mouse. It has been validated for ELISA and WB.

Quick Overview for AMNLS antibody (ABIN7227278)

Target: AMNLS (LOC101452581) (Protein Amnionless (LOC101452581))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMNLS antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-AMNLS Antibody

Purpose: Rabbit Anti-AMNLS Polyclonal Antibody

Specificity: The antibody detects endogenous levels of AMNLS protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human AMNLS protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for AMNLS

Target: AMNLS (LOC101452581) (Protein Amnionless (LOC101452581))

Alternative Name: AMNLS

Background: Protein amnionlessAmnion Associated Transmembrane Protein encoded by AMN is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila.

Molecular Weight: 49kD

Gene ID: 81693

UniProt: Q9BXJ7