PKIA antibody (AA 10-90)

Catalog No. ABIN7223454

The Rabbit Polyclonal anti-PKIA antibody (ABIN7223454) specifically detects PKIA in ELISA, IHC and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PKIA antibody (AA 10-90) (ABIN7223454)

Target: PKIA (Protein Kinase (CAMP-Dependent, Catalytic) Inhibitor alpha (PKIA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKIA antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-PKIA Antibody

Binding Specificity: AA 10-90

Purpose: Rabbit Anti-Pki α Polyclonal Antibody

Specificity: Pki α Polyclonal Antibody detects endogenous levels of Pki α protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Pki alpha at AA range: 10-90

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PKIA

Target: PKIA (Protein Kinase (CAMP-Dependent, Catalytic) Inhibitor alpha (PKIA))

Alternative Name: Pki alpha

Background: PKIA, PRKACN1, cAMP-dependent protein kinase inhibitor alpha, PKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoformThe protein encoded by PKIA (protein kinase (cAMP-dependent, catalytic) inhibitor alpha) is a member of the cAMP-dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported.

Gene ID: 5569

UniProt: P61925

Pathways: Myometrial Relaxation and Contraction