PPP1R13B antibody (AA 630-680)

Catalog No. ABIN7227388

This anti-PPP1R13B antibody is a Rabbit Polyclonal antibody detecting PPP1R13B in ELISA and IHC (p). Suitable for Human.

Quick Overview for PPP1R13B antibody (AA 630-680) (ABIN7227388)

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R13B antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PPP1R13B Antibody

Binding Specificity: AA 630-680

Purpose: ASPP1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ASPP1

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human ASPP1 protein at AA range: 630-680

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:200), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PPP1R13B

Target: PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))

Alternative Name: ASPP1

Background: Rabbit Anti-ASPP1 Polyclonal Antibody,Apoptosis-stimulating of p53 protein 1, Protein phosphatase 1 regulatory subunit 13B,PPP1R13B encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. PPP1R13B (Protein Phosphatase 1 Regulatory Subunit 13B) is a Protein Coding gene. Among its related pathways are Activation of BH3-only proteins and TP53 Regulates Transcription of Cell Death Genes.,ASPP1

Gene ID: 23368

UniProt: Q96KQ4

Pathways: p53 Signaling