PPP1R16B antibody (AA 340-420)

Catalog No. ABIN7220952

The Rabbit Polyclonal anti-PPP1R16B antibody (ABIN7220952) specifically detects PPP1R16B in WB and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for PPP1R16B antibody (AA 340-420) (ABIN7220952)

Target: PPP1R16B (Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R16B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PPP1R16B Antibody

Binding Specificity: AA 340-420

Purpose: Rabbit Anti-TIMAP Polyclonal Antibody

Specificity: TIMAP Polyclonal Antibody detects endogenous levels of TIMAP protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human TIMAP at AA range: 340-420

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PPP1R16B

Target: PPP1R16B (Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B))

Alternative Name: TIMAP

Background: PPP1R16B, ANKRD4, KIAA0823, Protein phosphatase 1 regulatory inhibitor subunit 16B, Ankyrin repeat domain-containing protein 4, CAAX box protein TIMAP, TGF-beta-inhibited membrane-associated protein, hTIMAPThe protein phosphatase 1 regulatory subunit 16B encoded by PPP1R16B is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Molecular Weight: 64kD

Gene ID: 26051

UniProt: Q96T49