PPP1R3A antibody (AA 620-700)

Catalog No. ABIN7223370

This Rabbit Polyclonal antibody specifically detects PPP1R3A in WB and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for PPP1R3A antibody (AA 620-700) (ABIN7223370)

Target: PPP1R3A (Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-PPP1R3A Antibody

Binding Specificity: AA 620-700

Purpose: Rabbit Anti-PPP1R3A Polyclonal Antibody

Specificity: PPP1R3A Polyclonal Antibody detects endogenous levels of PPP1R3A protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human PPP1R3A at AA range: 620-700

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PPP1R3A

Target: PPP1R3A (Protein Phosphatase 1, Regulatory Subunit 3A (PPP1R3A))

Alternative Name: PPP1R3A

Background: PPP1R3A, PP1G, Protein phosphatase 1 regulatory subunit 3A, Protein phosphatase 1 glycogen-associated regulatory subunit, Protein phosphatase type-1 glycogen targeting subunit, RG1The glycogen-associated form of protein phosphatase-1 (PP1) derived from skeletal muscle is a heterodimer composed of a 37-kD catalytic subunit and a 124-kD targeting and regulatory subunit. PPP1R3A (protein phosphatase 1 regulatory subunit 3A) encodes the regulatory subunit which binds to muscle glycogen with high affinity, thereby enhancing dephosphorylation of glycogen-bound substrates for PP1 such as glycogen synthase and glycogen phosphorylase kinase.

Molecular Weight: 140kD

Gene ID: 5506

UniProt: Q16821

Pathways: Cellular Glucan Metabolic Process