PPME1 antibody (AA 220-300)

Catalog No. ABIN7230756

This Rabbit Polyclonal antibody specifically detects PPME1 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PPME1 antibody (AA 220-300) (ABIN7230756)

Target: PPME1 (Protein Phosphatase Methylesterase 1 (PPME1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPME1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PPME1 Antibody

Binding Specificity: AA 220-300

Purpose: Rabbit Anti-PPME1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PPME1 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PPME1 protein at AA range: 220-300

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PPME1

Target: PPME1 (Protein Phosphatase Methylesterase 1 (PPME1))

Alternative Name: PPME1

Background: Protein phosphatase methylesterase 1, PME-1PPME1 (Protein Phosphatase Methylesterase 1) is a Protein Coding gene. Diseases associated with PPME1 include Malignant Glioma. PPME1 encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants.

Molecular Weight: 42kD

Gene ID: 51400

UniProt: Q9Y570

Pathways: Methionine Biosynthetic Process