PRC1 antibody (pThr481)

Catalog No. ABIN7230766

This Rabbit Polyclonal antibody specifically detects PRC1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for PRC1 antibody (pThr481) (ABIN7230766)

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PRC1 Antibody

Binding Specificity: pThr481

Purpose: PRC1 (Phospho-Thr481) Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PRC1Phospho occurs at Thr481

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human PRC1 (Phospho-Thr481) Polyclonal Antibody protein at AA range: 481

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for PRC1

Target: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Alternative Name: PRC1

Background: Rabbit Anti-PRC1 (Phospho-Thr481) Polyclonal Antibody,Protein regulator of cytokinesis 1,PRC1 encodes a protein that is involved in cytokinesis. The protein is present at high levels during the S and G2/M phases of mitosis but its levels drop dramatically when the cell exits mitosis and enters the G1 phase. It is located in the nucleus during interphase, becomes associated with mitotic spindles in a highly dynamic manner during mitosis, and localizes to the cell mid-body during cytokinesis. This protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants. PRC1 (Protein Regulator Of Cytokinesis 1) is a Protein Coding gene. Among its related pathways are Semaphorin interactions and Cytoskeletal Signaling.,PRC1

Molecular Weight: observerd band 72kDa

Gene ID: 9055

UniProt: O43663