PROS1 antibody (AA 20-100)

Catalog No. ABIN7230792

The Rabbit Polyclonal anti-PROS1 antibody is suitable to detect PROS1 in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for PROS1 antibody (AA 20-100) (ABIN7230792)

Target: PROS1 (PROS) (Protein S (PROS))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PROS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PROS1 Antibody

Binding Specificity: AA 20-100

Purpose: Rabbit Anti-PROS Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PROS protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PROS protein at AA range: 20-100

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PROS1

Target: PROS1 (PROS) (Protein S (PROS))

Alternative Name: PROS

Background: Vitamin K-dependent protein SPROS1 encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in PROS1 result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.

Molecular Weight: 74kD

Gene ID: 5627

UniProt: P07225