SPDEF/PSE antibody (AA 140-220)

Catalog No. ABIN7231488

The Rabbit Polyclonal anti-SPDEF/PSE antibody has been validated for ELISA and WB. It is suitable to detect SPDEF/PSE in samples from Human and Mouse.

Quick Overview for SPDEF/PSE antibody (AA 140-220) (ABIN7231488)

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPDEF/PSE antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-SPDEF/PSE Antibody

Binding Specificity: AA 140-220

Purpose: SPDEF Polyclonal Antibody

Specificity: The antibody detects endogenous levels of SPDEF protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human SPDEF protein at AA range: 140-220

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for SPDEF/PSE

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Alternative Name: SPDEF

Background: Rabbit Anti-SPDEF Polyclonal Antibody,SAM pointed domain-containing Ets transcription factor, Prostate epithelium-specific Ets transcription factor, Prostate-specific Ets, Prostate-derived Ets factor,The protein encoded by SPDEF belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for SPDEF.,SPDEF

Molecular Weight: observerd band 36kDa

Gene ID: 25803

UniProt: O95238