PRPF40A antibody (AA 450-530)

Catalog No. ABIN7230762

The Rabbit Polyclonal anti-PRPF40A antibody (ABIN7230762) specifically detects PRPF40A in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for PRPF40A antibody (AA 450-530) (ABIN7230762)

Target: PRPF40A (PRP40 Pre-mRNA Processing Factor 40 Homolog A (PRPF40A))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRPF40A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PRPF40A Antibody

Binding Specificity: AA 450-530

Purpose: Rabbit Anti-PR40A Polyclonal Antibody

Specificity: The antibody detects endogenous levels of PR40A protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human PR40A protein at AA range: 450-530

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PRPF40A

Target: PRPF40A (PRP40 Pre-mRNA Processing Factor 40 Homolog A (PRPF40A))

Alternative Name: PR40A

Background: Pre-mRNA-processing factor 40 homolog A, Fas ligand-associated factor 1, Formin-binding protein 11, Formin-binding protein 3, Huntingtin yeast partner A, Huntingtin-interacting protein 10, HIP-10, Huntingtin-interacting protein A, Renal carcinoma antigen NY-REN-6PRPF40A (Pre-MRNA Processing Factor 40 Homolog A) is a Protein Coding gene. Diseases associated with PRPF40A include Rett Syndrome. Among its related pathways are mRNA Splicing - Major Pathway and Gene Expression. Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.

Molecular Weight: 105kD

Gene ID: 55660

UniProt: O75400