PTK6 antibody

Catalog No. ABIN7223794

The Rabbit Polyclonal anti-PTK6 antibody is suitable to detect PTK6 in samples from Human and Mouse. It has been validated for ELISA and IF.

Quick Overview for PTK6 antibody (ABIN7223794)

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTK6 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-PTK6 Antibody

Purpose: Rabbit Anti-Brk Polyclonal Antibody

Specificity: Brk Polyclonal Antibody detects endogenous levels of Brk protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Brk around the non-phosphorylation site of Y447

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications,

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for PTK6

Target: PTK6 (PTK6 Protein tyrosine Kinase 6 (PTK6))

Alternative Name: Brk

Background: PTK6, BRK, Protein-tyrosine kinase 6, Breast tumor kinase, Tyrosine-protein kinase BRKThe protein encoded by PTK6 (protein tyrosine kinase 6) is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of PTK6 in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of PTK6 has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.

Gene ID: 5753

UniProt: Q13882