RSPO2 antibody

Catalog No. ABIN7231192

The Rabbit Polyclonal anti-RSPO2 antibody is suitable to detect RSPO2 in samples from Human and Mouse. It has been validated for WB and ELISA.

Quick Overview for RSPO2 antibody (ABIN7231192)

Target: RSPO2 (R-Spondin 2 (RSPO2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RSPO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RSPO2 Antibody

Purpose: Rabbit Anti-RSPO2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RSPO2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RSPO2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RSPO2

Target: RSPO2 (R-Spondin 2 (RSPO2))

Alternative Name: RSPO2

Background: R-spondin-2, Roof plate-specific spondin-2, hRspo2RSPO2 encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants.

Molecular Weight: 26kD

Gene ID: 340419

UniProt: Q6UXX9