RAB11FIP2 antibody (AA 310-390)
Quick Overview for RAB11FIP2 antibody (AA 310-390) (ABIN7220550)
Target
See all RAB11FIP2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 310-390
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Purpose
- Rab11-FIP2 Polyclonal Antibody
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Specificity
- Rab11-FIP2 Polyclonal Antibody detects endogenous levels of Rab11-FIP2 protein.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human Rab11-FIP2 at AA range: 310-390
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- RAB11FIP2 (RAB11 Family Interacting Protein 2 (Class I) (RAB11FIP2))
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Alternative Name
- Rab11-FIP2
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Background
- Rabbit Anti-Rab11-FIP2 Polyclonal Antibody,RAB11FIP2, KIAA0941, Rab11 family-interacting protein 2, Rab11-FIP2, NRip11,A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.,Rab11 family-interacting protein 2
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Molecular Weight
- observerd band 58kDa
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Gene ID
- 22841
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UniProt
- Q7L804
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Pathways
- Hormone Transport, Carbohydrate Homeostasis
Target
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