RAB13 antibody (AA 40-120)

Catalog No. ABIN7230870

This Rabbit Polyclonal antibody specifically detects RAB13 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RAB13 antibody (AA 40-120) (ABIN7230870)

Target: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAB13 Antibody

Binding Specificity: AA 40-120

Purpose: Rabbit Anti-RAB13 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RAB13 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RAB13 protein at AA range: 40-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RAB13

Target: RAB13 (RAB13, Member RAS Oncogene Family (RAB13))

Alternative Name: RAB13

Background: Ras-related protein Rab-13, Cell growth-inhibiting gene 4 proteinRAB13 (RAB13, Member RAS Oncogene Family) is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for RAB13. A pseudogene associated with RAB13 is located on chromosome 12.

Molecular Weight: 22kD

Gene ID: 5872

UniProt: P51153

Pathways: Cell-Cell Junction Organization