RAB21 antibody (AA 60-140)

Catalog No. ABIN7230882

This Rabbit Polyclonal antibody specifically detects RAB21 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for RAB21 antibody (AA 60-140) (ABIN7230882)

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB21 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAB21 Antibody

Binding Specificity: AA 60-140

Purpose: Rabbit Anti-RAB21 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RAB21 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RAB21 protein at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RAB21

Target: RAB21 (RAB21, Member RAS Oncogene Family (RAB21))

Alternative Name: RAB21

Background: Ras-related protein Rab-21RAB21 (RAB21, Member RAS Oncogene Family) belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of RAB21 is associated with a poor prognosis for glioma patients. RAB21 is downregulated by the tumor suppressor miR-200b and miRNA-200b is itself downregulated in glioma tissues.

Molecular Weight: 24kD

Gene ID: 23011

UniProt: Q9UL25