RAB23 antibody (AA 120-200)
Quick Overview for RAB23 antibody (AA 120-200) (ABIN7230884)
Target
See all RAB23 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 120-200
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Purpose
- Rabbit Anti-RAB23 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of RAB23 protein
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Immunogen
- Synthesized peptide derived from part region of human RAB23 protein at AA range: 120-200
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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Expiry Date
- 12 months
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- RAB23 (RAB23, Member RAS Oncogene Family (RAB23))
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Alternative Name
- RAB23
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Background
- Ras-related protein Rab-23RAB23 (RAB23, Member RAS Oncogene Family) encodes a small GTPase of the Ras superfamily. Rab proteins are involved in the regulation of diverse cellular functions associated with intracellular membrane trafficking, including autophagy and immune response to bacterial infection. The encoded protein may play a role in central nervous system development by antagonizing sonic hedgehog signaling. Disruption of RAB23 has been implicated in Carpenter syndrome as well as cancer. Alternative splicing results in multiple transcript variants.
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Molecular Weight
- 26kD
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Gene ID
- 51715
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UniProt
- Q9ULC3
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Pathways
- Tube Formation
Target
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