RAB3GAP1 antibody (AA 510-590)

Catalog No. ABIN7216712

This Rabbit Polyclonal antibody specifically detects RAB3GAP1 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RAB3GAP1 antibody (AA 510-590) (ABIN7216712)

Target: RAB3GAP1 (RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAB3GAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RAB3GAP1 Antibody

Binding Specificity: AA 510-590

Purpose: Rabbit Anti-Rab 3 GAP p130 Polyclonal Antibody

Specificity: Rab 3 GAP p130 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p130 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Rab 3 GAP p130 at AA range: 510-590

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:40000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RAB3GAP1

Target: RAB3GAP1 (RAB3 GTPase Activating Protein Subunit 1 (Catalytic) (RAB3GAP1))

Alternative Name: Rab 3 GAP p130

Background: RAB3GAP1, KIAA0066, RAB3GAP, Rab3 GTPase-activating protein catalytic subunit, RAB3 GTPase-activating protein 130 kDa subunit, Rab3-GAP p130, Rab3-GAPRAB3GAP1 encodes the catalytic subunit of a Rab GTPase activating protein. RAB3 GTPase activating protein catalytic subunit 1 forms a heterodimer with a non-catalytic subunit to specifically regulate the activity of members of the Rab3 subfamily of small G proteins. RAB3 GTPase activating protein catalytic subunit 1 mediates the hydrolysis of GTP bound Rab3 to the GDP bound form. Mutations in RAB3GAP1 are associated with Warburg micro syndrome. Alternate splicing results in multiple transcript variants.

Molecular Weight: 117kD

Gene ID: 22930

UniProt: Q15042