RALGDS antibody (AA 130-210)

Catalog No. ABIN7228694

The Rabbit Polyclonal anti-RALGDS antibody (ABIN7228694) specifically detects RALGDS in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for RALGDS antibody (AA 130-210) (ABIN7228694)

Target: RALGDS (Ral Guanine Nucleotide Dissociation Stimulator (RALGDS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RALGDS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RALGDS Antibody

Binding Specificity: AA 130-210

Purpose: Rabbit Anti-GNDS Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GNDS protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GNDS protein at AA range: 130-210

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RALGDS

Target: RALGDS (Ral Guanine Nucleotide Dissociation Stimulator (RALGDS))

Alternative Name: GNDS

Background: Ral guanine nucleotide dissociation stimulator, RalGDS, Ral guanine nucleotide exchange factor, RalGEFRALGDS (Ral Guanine Nucleotide Dissociation Stimulator) is a Protein Coding gene. Diseases associated with RALGDS include Aortic Valve Insufficiency and Afibrinogenemia, Congenital. Among its related pathways are p38MAPK events and Phospholipase-C Pathway. Guanine nucleotide dissociation stimulators (GDSs, or exchange factors), such as RALGDS, are effectors of Ras-related GTPases that participate in signaling for a variety of cellular processes.

Molecular Weight: 100kD

Gene ID: 5900

UniProt: Q12967

Pathways: Neurotrophin Signaling Pathway