REPS2 antibody (AA 390-470)
Quick Overview for REPS2 antibody (AA 390-470) (ABIN7230998)
Target
See all REPS2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 390-470
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Purpose
- REPS2 Polyclonal Antibody
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Specificity
- The antibody detects endogenous levels of REPS2 protein
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Purification
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human REPS2 protein at AA range: 390-470
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Isotype
- IgG
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Application Notes
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Comment
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Primary Antibody
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- REPS2 (RALBP1 Associated Eps Domain Containing Protein 2 (REPS2))
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Alternative Name
- REPS2
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Background
- Rabbit Anti-REPS2 Polyclonal Antibody,RalBP1-associated Eps domain-containing protein 2, Partner of RalBP1, RalBP1-interacting protein 2,The product of REPS2 (RALBP1 Associated Eps Domain Containing 2) is part of a protein complex that regulates the endocytosis of growth factor receptors. The encoded protein directly interacts with a GTPase activating protein that functions downstream of the small G protein Ral. Its expression can negatively affect receptor internalization and inhibit growth factor signaling. Multiple transcript variants encoding different isoforms have been found for REPS2.,REPS2
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Molecular Weight
- observerd band 72kDa
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Gene ID
- 9185
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UniProt
- Q8NFH8
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Pathways
- EGFR Signaling Pathway
Target
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