RANBP17 antibody (AA 120-200)

Catalog No. ABIN7224328

The Rabbit Polyclonal anti-RANBP17 antibody is suitable to detect RANBP17 in samples from Human and Mouse. It has been validated for WB and IHC.

Quick Overview for RANBP17 antibody (AA 120-200) (ABIN7224328)

Target: RANBP17 (RAN Binding Protein 17 (RANBP17))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RANBP17 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-RANBP17 Antibody

Binding Specificity: AA 120-200

Purpose: Rabbit Anti-Ran BP-17 Polyclonal Antibody

Specificity: Ran BP-17 Polyclonal Antibody detects endogenous levels of Ran BP-17 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Ran BP-17 at AA range: 120-200

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RANBP17

Target: RANBP17 (RAN Binding Protein 17 (RANBP17))

Alternative Name: Ran BP-17

Background: RANBP17, Ran-binding protein 17The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex, see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-17 is a member of the importin-beta superfamily of nuclear transport receptors.

Molecular Weight: 125kD

Gene ID: 64901

UniProt: Q9H2T7

Pathways: Protein targeting to Nucleus