RAPGEF2 antibody (AA 190-270)

Catalog No. ABIN7231162

This anti-RAPGEF2 antibody is a Rabbit Polyclonal antibody detecting RAPGEF2 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for RAPGEF2 antibody (AA 190-270) (ABIN7231162)

Target: RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPGEF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAPGEF2 Antibody

Binding Specificity: AA 190-270

Purpose: RPGF2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RPGF2 protein

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human RPGF2 protein at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Comment:

Primary Antibody

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Target Details for RAPGEF2

Target: RAPGEF2 (Rap Guanine Nucleotide Exchange Factor (GEF) 2 (RAPGEF2))

Alternative Name: RPGF2

Background: Rabbit Anti-RPGF2 Polyclonal Antibody,Rap guanine nucleotide exchange factor 2, Cyclic nucleotide ras GEF, CNrasGEF, Neural RAP guanine nucleotide exchange protein, nRap GEP, PDZ domain-containing guanine nucleotide exchange factor 1, PDZ-GEF1, RA-GEF-1, Ras/Rap1-associating GEF-1,RAPGEF2 (Rap Guanine Nucleotide Exchange Factor 2) is a Protein Coding gene. Among its related pathways are RET signaling and G-protein signaling_Rap1A regulation pathway. Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF2, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.,RPGF2

Molecular Weight: observerd band 164kDa

Gene ID: 9693

UniProt: Q9Y4G8

Pathways: Neurotrophin Signaling Pathway