RAPGEF4 antibody (AA 240-320)

Catalog No. ABIN7231164

The Rabbit Polyclonal anti-RAPGEF4 antibody is suitable to detect RAPGEF4 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for RAPGEF4 antibody (AA 240-320) (ABIN7231164)

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAPGEF4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAPGEF4 Antibody

Binding Specificity: AA 240-320

Purpose: Rabbit Anti-RPGF4 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RPGF4 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RPGF4 protein at AA range: 240-320

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RAPGEF4

Target: RAPGEF4 (Rap Guanine Nucleotide Exchange Factor (GEF) 4 (RAPGEF4))

Alternative Name: RPGF4

Background: Rap guanine nucleotide exchange factor 4, Exchange factor directly activated by cAMP 2, Exchange protein directly activated by cAMP 2, EPAC 2, cAMP-regulated guanine nucleotide exchange factor II, cAMP-GEFIIRAPGEF4 (Rap Guanine Nucleotide Exchange Factor 4) is a Protein Coding gene. Diseases associated with RAPGEF4 include Lesch-Nyhan Syndrome and Acrodysostosis. Among its related pathways are Rap1 signalling and Metabolism. GO annotations related to RAPGEF4 include guanyl-nucleotide exchange factor activity and Ras GTPase binding. An important paralog of RAPGEF4 is RAPGEF3.

Molecular Weight: 111kD

Gene ID: 11069

UniProt: Q8WZA2

Pathways: Hormone Transport, Smooth Muscle Cell Migration