RAP1B antibody (AA 110-190)

Catalog No. ABIN7230936

This Rabbit Polyclonal antibody specifically detects RAP1B in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RAP1B antibody (AA 110-190) (ABIN7230936)

Target: RAP1B (RAP1B, Member of RAS Oncogene Family (RAP1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RAP1B Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-RAP1B Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RAP1B protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RAP1B protein at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RAP1B

Target: RAP1B (RAP1B, Member of RAS Oncogene Family (RAP1B))

Alternative Name: RAP1B

Background: GTP-binding protein smg p21BRAP1B encodes a member of the RAS-like small GTP-binding protein superfamily. Members of this family regulate multiple cellular processes including cell adhesion and growth and differentiation. This protein localizes to cellular membranes and has been shown to regulate integrin-mediated cell signaling. This protein also plays a role in regulating outside-in signaling in platelets. Alternate splicing results in multiple transcript variants. Pseudogenes of RAP1B are found on chromosomes 3, 5, 6 and 9.

Molecular Weight: 20kD

Gene ID: 5908

UniProt: P61224

Pathways: CXCR4-mediated Signaling Events, Signaling of Hepatocyte Growth Factor Receptor