RHOQ antibody (AA 60-140)

Catalog No. ABIN7231052

The Rabbit Polyclonal anti-RHOQ antibody is suitable to detect RHOQ in samples from Human, Rat and Mouse. It has been validated for WB and ELISA.

Quick Overview for RHOQ antibody (AA 60-140) (ABIN7231052)

Target: RHOQ (Ras Homolog Gene Family, Member Q (RHOQ))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHOQ antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RHOQ Antibody

Binding Specificity: AA 60-140

Purpose: Rabbit Anti-RHOQ Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RHOQ protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RHOQ protein at AA range: 60-140

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RHOQ

Target: RHOQ (Ras Homolog Gene Family, Member Q (RHOQ))

Alternative Name: RHOQ

Background: Rho-related GTP-binding protein RhoQ, Ras-like protein TC10, Ras-like protein family member 7ARHOQ (Ras Homolog Family Member Q) encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14.

Molecular Weight: 22kD

Gene ID: 23433

UniProt: P17081