RASA2 antibody

Catalog No. ABIN7230948

The Rabbit Polyclonal anti-RASA2 antibody is suitable to detect RASA2 in samples from Human, Mouse and Rat. It has been validated for ELISA and WB.

Quick Overview for RASA2 antibody (ABIN7230948)

Target: RASA2 (RAS P21 Protein Activator 2 (RASA2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASA2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-RASA2 Antibody

Purpose: Rabbit Anti-RASA2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RASA2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RASA2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RASA2

Target: RASA2 (RAS P21 Protein Activator 2 (RASA2))

Alternative Name: RASA2

Background: Ras GTPase-activating protein 2, GTPase-activating protein 1m, GAP1mRAS P21 Protein Activator 2 encoded by RASA2 is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Alternative splicing results in multiple transcript variants.

Molecular Weight: 93kD

Gene ID: 5922

UniProt: Q15283