RIT2 antibody

Catalog No. ABIN7231070

The Rabbit Polyclonal anti-RIT2 antibody is suitable to detect RIT2 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for RIT2 antibody (ABIN7231070)

Target: RIT2 (Ras-Like Without CAAX 2 (RIT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIT2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-RIT2 Antibody

Purpose: Rabbit Anti-RIT2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of RIT2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human RIT2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RIT2

Target: RIT2 (Ras-Like Without CAAX 2 (RIT2))

Alternative Name: RIT2

Background: GTP-binding protein Rit2, Ras-like protein expressed in neurons, Ras-like without CAAX protein 2RIN belongs to the RAS (HRAS, MIM 190020) superfamily of small GTPases (Shao et al. 1999 [PubMed 10545207]). RIT2 (Ras Like Without CAAX 2) is a Protein Coding gene. Diseases associated with RIT2 include Ehrlichiosis and Parkinson Disease Susceptibility. Among its related pathways are RET signaling and Neurotrophic factor-mediated Trk receptor signaling.

Molecular Weight: 23kD

Gene ID: 6014

UniProt: Q99578

Pathways: Neurotrophin Signaling Pathway