RERG antibody (AA 70-150)

Catalog No. ABIN7225492

The Rabbit Polyclonal anti-RERG antibody (ABIN7225492) specifically detects RERG in ELISA, IHC and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for RERG antibody (AA 70-150) (ABIN7225492)

Target: RERG (RAS-Like, Estrogen-Regulated, Growth Inhibitor (RERG))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RERG antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-RERG Antibody

Binding Specificity: AA 70-150

Purpose: Rabbit Anti-RERG Polyclonal Antibody

Specificity: RERG Polyclonal Antibody detects endogenous levels of RERG protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human RERG at AA range: 70-150

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for RERG

Target: RERG (RAS-Like, Estrogen-Regulated, Growth Inhibitor (RERG))

Alternative Name: RERG

Background: RERG, Ras-related and estrogen-regulated growth inhibitorMembers of the Ras superfamily of small GTP-binding proteins are critical mediators of diverse cell signaling pathways, including those leading to cell proliferation, cytoskeletal organization and secretion. RERG (RAS-like, estrogen-regulated, growth inhibitor) is a 199 amino acid protein that localizes to the cytoplasm and belongs to the Ras subfamily of small GTPases. Expressed in pancreas, liver, skin, lung, brain, kidney and heart tissue, RERG possesses intrinsic GTPase activity and is able to bind both GDP and GTP and, when overexpressed, may reduce overall tumorigenic potential. RERGL, also known as ras-related and estrogen-regulated growth inhibitor-like protein, is a 205 amino acid protein that belongs to the small GTPase superfamily as well as the Ras family. RERGL binds GDP/GTP and may possess intrinsic GTPase activity. The RERGL gene is conserved in chimpanzee, dog, mouse, rat, chicken, zebrafish and mosquito, and maps to human chromosome 12p12.3.

Gene ID: 85004

UniProt: Q96A58